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What is duloxetine?
Cymbalta is the brand name for the drug duloxetine which is a Serotonin- norepinephrine reuptake inhibitor that is manufactured by the pharmaceutical company Eli Lily.
Cymbalta is used as an antidepressant.
This medicine functions by affecting chemicals in the brain and nervous system which leads to depression in patients. It therefore functions in balancing these chemicals and their effects.
Cymbalta is very effective for the treatment of major depressive disorder. It is also effective for the treatment of generalized anxiety disorder (GAD). Besides that, it is known to relieve pain that results from diabetic neuropathy and fibromyalgia.
Why is duloxetine prescribed?
Cymbalta is an antidepressant and it is used to treat some major depressive disorders and it is also used in the treatment of general anxiety disorders. Because of its action that has to do with the brain and nervous tissues it is also often used to treat chronic pain that is as a result of nervous damage in patients who suffer from diabetes for a long time, pain due to chronic musculoskeletal disturbance and pain from osteoarthritis. This drug is also indicated for the treatment of chronic pain of the lower back.
What are the duloxetine side effects?
The very duloxetine common side effects that come with the use of Cymbalta are allergic reactions which can be seen as hives, breathing difficulty, swollen lips, throat or tongue, nausea, feeling of dryness in the mouth, tiredness and easily fatigued, drowsiness and sleepiness, constipation, sweating is increased, pain attacks, mood swings, restlessness, increased depression, agitation, impulsive feeling, insomnia, irritability, becoming more aggressive, becoming very hyperactive both physically and mentally, hostile, having suicidal thoughts or thoughts that is aimed at self-harm, loss of appetite and dizziness.
When you are on Cymbalta for the treatment of any of the conditions mentioned above and you have a constant repetition or these symptoms you should notify your doctor who will ensure you are given the best attention to curb the symptoms which are actually the side effects of Cymbalta.
What is the proper duloxetine dosage?
The duloxetine dosage is different for every patient and depends on the condition of the patient. So, it is recommended to follow the advice of a professional. However here are some general dosages:
Dose for pain:
The general dose of neuropathic pain caused by diabetic peripheral neuropathy and for chronic musculoskeletal pain and for chronic low back pain is 60 mg in a day.
However, it may vary for patients. Some patient should start with a low dosage. More than 120 mg a day is harmful for health, but more than 60 mg in a day usually has no extra benefit.
Dose for depression:
Dose for depression should be increased gradually from 40 mg daily to 60 mg. 40 mg dose should be in 20mg doses twice per day. 60 mg dose could be taken once as a 60 mg tablet or twice as 30 mg tablet.
Dose for anxiety:
It may be given 60 mg once in a day. But it can be increased with 30 mg. Maximum 120 mg in a day can be prescribed. Who has a tolerability concern should start with 30 mg a day. More than 120 mg a day is harmful for health, but more than 60 mg in a day usually has no extra benefit. There is no strong evidence that more than 60 mg in a day has additional benefit, although 120 mg in a day is safe. Be careful not to overdose.
Dose for fibromyalgia:
The initial dose is 30 mg a weak. The usual dose however is 60 mg a week.
Who should not take duloxetine?
The anti-depressant can be used by most people but it is strictly prohibited for people who are on other antidepressant from the group of MAOI (monoamine oxidase inhibitor). The use of Cymbalta is also contraindicated for patients with severe narrow angle glaucoma that is uncontrolled. It is always good to ask your doctor before you take any drug that crosses the blood brain barrier if you have any liver or kidney diseases because some of these drugs can be tasking on these organs and therefore have the capacity to cause more problems to the body. Cymbalta is one of such drugs that you should let your doctor know you want to start the therapy if you do have any kidney or liver disease.
How does duloxetine withdrawal happen?
Do you want to stop with duloxetine? Then it is best to consult your pharmacist or doctor. He will then make a schedule so you can stop with this medication without experiencing too much side effect. You will lower your dose in small steps so that you do not suddenly suffer from withdrawal symptoms. You will then receive a slightly lower dose every week.
It often takes a total of 2 to 8 weeks to stop with duloxetine. How quickly you can stop depends on whether you have any complaints. Therefore, it is advisable to discuss everything with your doctor to see how you react at each step. He can help you if you have any complaints.
Are you suffering from depression, anxiety or panic again? Or do you suffer from withdrawal symptoms? Discuss this with your doctor or pharmacist.
What are the precautions regarding duloxetine?
Blood sugar levels
Blood sugar levels may be affected by using duloxetine, so you have to check your blood sugar regularly. You also have to inform your doctor about this drug before surgery. Result of taking this drug may also cause bleeding for older adults.
Drinking
Duloxetine and alcohol have several moderate interactions which increases the risk of liver damage. You should avoid drinking alcohol (Ethanol) while using duloxetine.
Driving
Dizzy or drowsiness may be occurred as consequent of using these drugs. So, driving, using heavy machinery or doing other activities that require consciousness is not recommended if you are not sure that you can perform that activities without making any accident.
Do not drive a car if the dosage increases.
Do not drive a car again until you have taken the same dose for 1 week.
After 1 week most people have gotten used to the effects. You may then drive again. But only do so if you no longer suffer from the side effects.
Pregnancy
During pregnancy this medicine you should try to avoid this drug, only use it if really needed. It may be harmful for an unborn child. There is no clear report that shows that it can harm during pregnancy. But there is some experience that shows it may cause breathing difficulties, muscle stiffness to a new baby whose mother uses this drug during the last three months of pregnancy period. If you see these symptoms to a new born baby then immediately discuss this matter to a professional.
Withdrawal
Do not stop duloxetine suddenly without discussing your doctor. It may cause some mood disorder.
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