Armodafinil (Nuvigil)

Description

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What is Armodafinil?

Armodafinil is an FDA-approved prescription drug used to treat sleep disorders that result in excessive sleepiness. like narcolepsy, obstructive sleep apnea, and shift work disorder. It belongs to the family of drugs known as wakefulness-promoting agents and works by stimulating certain brain areas that are responsible for staying awake. 

It is sold under the brand name Nuvigil, however there are also generic medications available. Generic medications are typically cheaper than their brand name variant.

How does Armodafinil work?

Armodafinil is a medicine that is capable of promoting wakefulness. It is an oral medicine similar to Modafinil (Provigil). It improves wakefulness like amphetamines, by stimulating the brain, even though the exact mechanism of the process is not yet known. Armodafinil probably works by increasing dopamine (a chemical neurotransmitter that is used by nerves to communicate with each other) content in your brain. It also reduces the reuptake of dopamine in nerves.

Armodafinil dosage: which Armodafinil dose is right for me?

The recommended dosage may vary depending on the condition being treated and the individual’s response to the medication.

• For narcolepsy or obstructive sleep apnea, the recommended starting dose of armodafinil is usually 150 mg once daily in the morning. The dose can be increased to 250 mg per day if necessary.
• For shift work sleep disorder, the recommended dose is 150 mg taken once daily, approximately one hour before the start of the work shift.

It is important to follow the dosage instructions provided by your healthcare provider and not exceed the recommended dose without consulting with them first.

Armodafinil side effects: which side effects does Armodafinil have?

Like all medications, Armodafinil may cause side effects. Possible side effects include:

• Headache
• Nausea
• Dizziness
• Dry mouth
• Insomnia
• Anxiety
• Nervousness
• Confusion
• Agitation
• Diarrhea

If you experience any of these side effects, they are usually mild and go away on their own. However, if these side effects persist or worsen, you should contact your healthcare provider.

More serious side effects of armodafinil are rare, but they can occur. These include:

• Allergic reactions, such as rash, itching, swelling of the face, tongue, throat, or trouble breathing
• Hallucinations
• Depression or other mental health problems
• Suicidal thoughts or actions
• Chest pain
• Irregular heartbeat
• Severe skin reactions, such as Stevens-Johnson syndrome or toxic epidermal necrolysis

If you experience any of these serious side effects, seek medical attention immediately.

It’s essential to inform your doctor or healthcare provider about all medications you are taking before starting armodafinil, as well as any pre-existing medical conditions you have.

With which medicines does Armodafinil interact?

Armodafinil has the capacity to increase or decrease the activity level of some enzymes in the liver, which are responsible for the elimination of other medicines. So, it can result in decreased levels of other medicines and reduce their effectiveness. It may also increase the level of other medicines and thereby increase their toxicity. Armodafinil activity should be monitored closely if it is used with other medicines.

It can reduce the effectiveness of medicines like cyclosporine (Sandimmune), ethinyl estradiol (Estrace, Climara, Estraderm, Menostar) (present in many birth control pills), midazolam (Versed), and triazolam (Halcion).

It can increase the effectiveness or toxicity in medicines like omeprazole (Prilosec), warfarin (Coumadin), diazepam (Valium), propranolol (Inderal), imipramine (Tofranil), desipramine (Norpramin), clomipramine (Anafranil), phenytoin (Dilantin) and mephenytoin (Mesantoin).

Medicines like Carbamazepine (Tegretol), phenobarbital, and rifampin (Rifadin) can reduce the effectiveness of Armodafinil as they increase the elimination of armodafinil by the liver. On the other hand, medicines like Ketoconazole (Nizoral), itraconazole (Sporanox) and erythromycin can increase the effectiveness of armodafinil is varied use its elimination by the liver. 

Armodafinil precautions and warnings

Like any medication, it is important to take necessary precautions and consider any warnings associated with the use of armodafinil. Here are some important precautions and warnings to be aware of:

• Allergic reactions: People who are allergic to this medication should not take this medication. Symptoms of an allergic reaction may include rash, hives, itching, difficulty breathing, and swelling of the face, tongue, or throat.
• Cardiovascular effects: This medication may increase blood pressure and heart rate. People with a history of cardiovascular disease or high blood pressure should discuss their medical history with their doctor before taking Armodafinil.
• Liver problems: This medication can cause liver damage, including elevated liver enzymes and liver failure.
• Pregnancy and breastfeeding: This medication may harm a developing fetus and should not be taken during pregnancy. It is also not recommended for use while breastfeeding.
• Abuse potential: This medication can be habit-forming and has potential for abuse. It should only be taken as prescribed by a doctor and never shared with others.

Overall, it is important to talk to your doctor about any medical conditions or medications you are taking before starting Armodafinil to determine if it is safe for you.

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